- Several film personalities who established themselves even before the previous seasons of Koffee with Karan made their first appearances on the show during this season including Salman Khan, Salim Khan, Aamir Khan, Kiran Rao, Akshay Kumar, Emraan Hashmi, Mahesh Bhatt, Anurag Kashyap, Juhi Chawla, Freida Pinto and Rohit Shetty.
- Several film personalities who have recently established themselves made their first appearances on the show during this season including Arjun Kapoor, Sidharth Malhotra, Varun Dhawan,Alia Bhatt, Nargis Fakhri, Ayan Mukerji, Aditya Roy Kapur, Shraddha Kapoor, and Parineeti Chopra.
- For the first time in the history of Koffee with Karan, it has happened that an episode has been moved to a late night slot due to some bold confessions made by guests, Nargis Fakhri and Freida Pinto.
- For the first time in the history of Koffee with Karan, it has happened that Shah Rukh Khan did not appear in any episode in the season.
|Episode 1||1 December||Salman Khan & Salim Khan|
|Episode 2||8 December||Kareena Kapoor Khan & Ranbir Kapoor|
|Episode 3||15 December||Aamir Khan & Kiran Rao|
|Episode 4||22 December||Ranveer Singh & Arjun Kapoor, Shanoo Sharma|
|Episode 5||29 December||Sidharth Malhotra, Varun Dhawan & Alia Bhatt|
|Episode 6||5 January||Priyanka Chopra & Deepika Padukone|
|Episode 7||12 January||Farhan Akhtar & Vidya Balan|
|Episode 8||19 January||Akshay Kumar|
|Episode 9||26 January||Emraan Hashmi & Mahesh Bhatt|
|Episode 10||2 February||Sonakshi Sinha & Shahid Kapoor|
|Episode 11||9 February||Anushka Sharma & Anurag Kashyap|
|Episode 12||16 February||Abhishek Bachchan & Farah Khan|
|Episode 13||23 February||Juhi Chawla & Madhuri Dixit|
|Episode 14||2 March||Freida Pinto & Nargis Fakhri|
|Episode 15||9 March||Aditya Roy Kapur & Shraddha Kapoor|
|Episode 16||16 March||Kajol & Ayan Mukerji|
|Episode 17||23 March||Rohit Shetty & Zoya Akhtar|
|Episode 18||30 March||Anil Kapoor & Sonam Kapoor|
|Episode 19||6 April||Parineeti Chopra & Alia Bhatt|
|Episode 20||13 April||Best of Koffee With Karan Season 4|